The research group funded by the Else Kröner Fresenius Foundation (spokesperson: Prof. Dr. med. Michael Lohoff) consists of scientists from the Philipps University of Marburg, the Johannes Gutenberg University of Mainz, the Julius Maximilian University of Würzburg and the German Rheumatism Research Center DRFZ in Berlin. The consortium has set itself the goal of finding new basic approaches for immune-therapies for chronic inflammatory diseases and infections. The projects are supported by an innovative immunodiagnostic technique, CyTOF, which can comprehensively type immune cells at the single cell level. The data obtained in the first phase in animals will be validated on patient samples in the second step. For this purpose, a project biobank has been established under the direction of CBBMR since 2018, in which biosamples from asthmatics, Crohn's disease patients, arthritic patients and healthy control persons are collected.