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Clinical Research Unit 325 "The Clinical Relevance of the Tumor Microenvironment - Interactions in Pancreatic Ductal Adenocarcinoma PDAC

The Marburg Clinical Research Unit, which has been funded by the DFG since 2018, aims to characterize the role of so-called stromal cells in pancreatic cancer and to use these results to derive new therapeutic approaches to this tumor disease, which has so far been difficult to treat. In particular, the research group focuses on immune cells that promote tumor growth on the one hand, but on the other hand have inhibitory effects on tumor development. In addition to basic experiments on animal material and cell lines, investigations are also carried out on human tumor samples. For this purpose, CBBMR has established a pancreatic tumor bank, in which tissue and blood samples from patients are also stored. Together with the project groups, a comprehensive cell culture and organoid bank is currently being set up for which the human tumor samples are specially prepared.
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